Professor Dominiczak is a world-leading cardiovascular scientist and clinical academic. She has published extensively in top peer-reviewed journals (over 550 publications, a h-index of 123 according to Web of Science). Between 2010 and 2020 she was Vice-Principal and Head of the College of Medical, Veterinary and Life Sciences at the University of Glasgow. She was the driving force behind the fundraising, development and delivery of the University’s clinical academic campus at the Queen Elizabeth University Hospital, where she led a triple helix partnership between academia, the NHS, and industry to accelerate innovation, maximize patient benefits and economic growth.

Dame Anna is a member of several editorial boards and, from 2012 - 2022, was Editor-in-Chief of Hypertension, journal of the American Heart Association. Currently, she is Editor-in Chief of Precision Medicine, a new Prism journal of the Cambridge Press.

In March 2020, Anna led the establishment of Lighthouse Laboratory in Glasgow to provide rapid Covid–19 diagnostics, and then was asked to become Director of Laboratories at the UK Department of Health and Social Care to lead all 10 Lighthouse Laboratories across the UK, the role she fulfilled until 2022.

In July 2022 Professor Dominiczak was appointed as Chief Scientist (Health) for the Scottish Government, where she leads and coordinates health research and innovation, working in partnership with the NHS, academia and industry to develop rapid translation and adoption of transformative innovations for the Scottish NHS.